Why are the causes of aging uncertain
In order to be able to evaluate the impact of interventions on aging, it is first necessary to understand the relationship between the pathogenesis of age-associated diseases such as cancer, diabetes or Alzheimer's to the fundamental molecular processes of aging. It seems conceivable that many disease risk factors depend on aging itself, which in turn seems to have more than one cause. Once these connections have been deciphered, hope could be nourished again.
Vijg, Jan; Campisi, Judith: Puzzles, promises and a cure for aging, in: Nature, Vol. 454, August 28, 2008, pp. 1065-1071. (doi: 10.1038 / nature07216)
Partridge, Linda; Gems, David: Benchmarks for aging studies, in: Nature, Vol. 450, November 8, 2007, pp. 165-167.
Hayflick, Leonard: Biological Aging Is No Longer an Unsolved Problem, in: Annals of the New York Academy of Sciences 1100: 1-13 (2007). (Doi: 10.1196 / annals.1395.001)
Rose, Michael R .: Can aging be stopped? In: Spectrum of Science. Dossier 04/08: Longevity
Behl, Christian: Molecular Foundations of Aging - An Introduction. In: Ganten / Ruckpaul (Ed.), Molecular Medicine Basics of Age-Specific Diseases, Berlin Heidelberg 2004, pp. 67-86.
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